
Numb for hours, often sorer for a day or two, then relief that builds over a week. Here is the normal script, the flare that scares everyone, and the limits worth knowing.
Cortisone injections generate more confused phone calls than any other treatment in a foot clinic, and it is because the first 48 hours routinely go in the opposite direction from what people expect. You leave the office feeling great, wake up the next day sorer than before the appointment, and reasonably conclude something went wrong. Usually nothing did. The anesthetic wore off on schedule, the steroid had not started yet, and you were standing in the well-documented gap between the two.
This guide lays out that sequence day by day, what a cortisone flare is and how to tell it from the rare infection, the activity rules that protect a temporarily pain-silenced foot, and the honest version of how long relief lasts and how many shots one spot should get.
Medically reviewed by Dr. Timothy Horak and Julia Shauger, board-certified podiatric specialists serving Homewood, South Chicago Heights & Mokena. Last reviewed August 2026.
Numb and comfortable for 4 to 8 hours, then commonly sore for 1 to 3 days (the cortisone flare), with real relief starting day 2 to 7 and peaking by two weeks. Walk normally, but skip sport and heavy days for about 48 hours. Soreness that settles is a flare; pain that escalates after day 2 with spreading redness or fever is a same-day call.
Not worrying: soreness for a day or two that then improves, a small bruise, facial flushing for a day, and, weeks later, a small patch of lightened skin or a shallow dimple at the site.
The condition being injected predicts the result better than anything about the shot itself.
| Condition | Typical relief | What the window is for |
|---|---|---|
| Plantar fasciitis | Weeks to a few months | Stretching, orthotics, and load changes that fix the cause |
| Morton's neuroma | Months; sometimes lasting | Wide shoes and metatarsal padding; some never need more |
| Arthritis (big toe, midfoot, ankle) | 6 weeks to several months | Stiff-soled footwear and activity adjustments; repeatable periodically |
| Bursitis / capsulitis | Often durable after one | Fixing the pressure source: shoes, padding, mechanics |
| Gout flare | Settles the flare in days | Getting uric acid managed so there is no next flare |
| Achilles tendon | Generally not injected | Steroid weakens tendon here; other treatments exist for a reason |
The pattern across every row: cortisone switches off inflammation, and it does that well. It does not change the mechanics that inflamed the tissue. When relief keeps wearing off, the message is not that you need a subscription to injections, it is that the mechanical cause is still running and needs a different tool.
The most practically important thing about a cortisone shot is not the flare or the rare infection. It is that for weeks afterward, the structure that hurt cannot protest properly. Pain is the system that stops you from overloading damaged tissue, and the injection deliberately silences it while changing nothing about the tissue's actual strength on day one.
This is why the plantar fascia and tendons get treated with respect around injections. A fascia that stops hurting is not a fascia that got stronger, and the known, documented way people rupture one is a hard month on a steroid-silenced foot. It is also why cortisone is essentially never injected into the Achilles itself, and why your podiatrist may pair a fascia injection with continued support rather than a return to full mileage.
The winning move is almost boringly simple: treat the relief as a window for rehab, not proof of cure. The stretching, the orthotic, the footwear change, the gradual load build, all of it works dramatically better in a foot that does not hurt, and that combination, not the injection alone, is what produces the endings where the pain never comes back.
Shot was for heel pain? Where an injection fits in the full plantar fasciitis timeline. How Long Does Plantar Fasciitis Take to Heal? →
Shot was for a neuroma? The full treatment ladder, including what comes if injections stop holding. Morton's Neuroma: Treatment and Recovery →
Shot was for a gout flare? Why the attack ending is the moment the real work starts. Gout Attack Timeline: How Long It Lasts →
Expect three acts. First, if the injection included local anesthetic, the area feels numb and often remarkably good for 4 to 8 hours; enjoy it, but do not let it talk you into a big evening on your feet. Second, as the numbing fades there is commonly a sore stretch of 1 to 3 days, sometimes including a genuine cortisone flare where the spot hurts more than before the shot. Third, the steroid itself starts working somewhere between day 2 and day 7, with the full effect landing by about two weeks. If nothing has improved at the two-week mark, tell your podiatrist rather than assuming shots do not work for you; a miss on location, a different diagnosis, or a condition that responds poorly to steroid are each useful information.
This is the cortisone flare, and it is the single most common cause of post-injection panic. Many steroid preparations are crystal suspensions, and in some people those crystals briefly irritate the tissue before the anti-inflammatory effect takes over, producing a spot that is angrier than it was before the needle. It affects a meaningful minority of injections, typically starts within 24 to 48 hours, and settles within 1 to 3 days with ice, rest, and ordinary pain relief. The distinction that matters is between a flare and an infection: a flare is sore but settles and the skin looks unremarkable; an infection escalates after day 2 to 3 with spreading redness, warmth, swelling, and sometimes fever, and it is rare but urgent. Sore-then-better is the flare script. Sore-then-worse with a red, hot joint is a call today.
Yes, ordinary walking is fine the same day and most people drive home from the appointment. What deserves restraint is everything above ordinary: running, court sports, long hikes, and heavy standing shifts are best avoided for roughly 48 hours, and for a weight-bearing structure like the plantar fascia many podiatrists prefer several easy days. There are two reasons. The mundane one is that the injected tissue is briefly irritated and loading it hard prolongs the sore phase. The subtler one is that the anesthetic and then the steroid mute your pain signal, and pain was the only thing stopping you from overloading a structure that is still mechanically fragile. This matters most for the plantar fascia and tendons, where the injection relieves the alarm without repairing the wiring, and a hard week on a silenced fascia is how ruptures happen.
Honest answer: anywhere from weeks to permanent, and the condition being injected predicts it better than anything else. For an acutely inflamed joint or a Morton's neuroma, one injection sometimes settles the problem for good, particularly when footwear and mechanics get fixed in the window the shot provides. For plantar fasciitis, studies consistently show good relief measured in weeks to a few months, with the underlying problem still needing the stretching, support, and load management to actually resolve. For arthritis, relief typically runs 6 weeks to several months and can be repeated periodically. The most useful way to think about it: cortisone reliably turns off inflammation, temporarily. Whether the pain returns depends on whether the thing that was inflaming the tissue is still happening. The shot buys a window; what you do inside the window decides the ending.
The commonly used guardrail is no more than 3 to 4 injections into any one site per year, with at least 6 weeks and preferably 3 months between them, and a hard rethink if the second injection did not produce durable benefit. The concern is real but often misstated: repeated steroid exposure can weaken tendons and the plantar fascia, thin the fat pad under the heel or ball of the foot (which is irreplaceable and does the cushioning you will want for the rest of your life), and in joints, frequent repeated injections may accelerate cartilage wear. This is also why cortisone is essentially never injected INTO the Achilles tendon and why fascia injections are placed carefully rather than casually repeated. A shot that keeps wearing off is not a schedule, it is a message: the diagnosis or the mechanics need attention, and options like orthotics, shockwave, physical therapy, or a surgical conversation exist for exactly that situation.
The urgent one is infection, which is rare but real: redness spreading from the injection site, increasing warmth and swelling, pain that escalates after day 2 to 3 rather than settling, fever or chills, or a joint that becomes too painful to move at all. Any of those is a same-day call, because an infected joint is an emergency. The non-urgent list worth knowing so it does not frighten you: a small patch of skin lightening or a dimple of fat thinning at the injection site can appear weeks later and is usually cosmetic; people with diabetes commonly see elevated blood sugar readings for several days after a steroid injection and should watch numbers a little more closely; and facial flushing for a day or two, more common in women, is harmless and self-resolving. A sudden pop or collapse of the arch weeks after a plantar fascia injection deserves prompt review, since fascia rupture is the known structural risk.
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An injection is a tool, not a plan. Our board-certified podiatrists diagnose the cause, use injections where they genuinely help, and fix the mechanics so relief lasts, across our Homewood, South Chicago Heights, and Mokena clinics.